New position:

LabEx Milieu Interieur Senior Data Scientist

Open position at Institut Pasteur (Paris, France)



Read our latest publications in Nature Immunology and PNAS and discover the factors that most affect our immune system




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Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors

Etienne Patin, Milena Hasan, Jacob Bergstedt, Vincent Rouilly et al. and The Milieu Intérieur Consortium

The quantification and characterization of circulating immune cells provide key indicators of human health and disease. To identify the relative effects of environmental and genetic factors on variation in the parameters of innate and adaptive immune cells in homeostatic conditions, we combined...

A Cross-Talk Between Microbiota-Derived Short-Chain Fatty Acids and the Host Mucosal Immune System Regulates Intestinal Homeostasis and Inflammatory Bowel Disease.

Gonçalves P, Araújo J, Di Santo JP

Gut microbiota has a fundamental role in the energy homeostasis of the host and is essential for proper "education" of the immune system. Intestinal microbial communities are able to ferment dietary fiber releasing short-chain fatty acids (SCFAs). The SCFAs, particularly butyrate (BT), regulate...


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