An annual two-weeks school in "Human Population Genomics and Genetic Epidemiology" has been created in the context of the Milieu Intérieur themes.
This course highlights the multidisciplinary approach of the Milieu Intérieur project in that it will provide the theoretical and practical basis of the project research questions; the use of population genetics and genetic epidemiology approaches to tackle major questions in human immunology, infectiology and public health.
The course integrates different partners of the project, including the Institut Pasteur, INSERM, and CNRS, and the main Parisian Universities, such as Paris Descartes (Paris V), Paris Pierre et Marie Curie (Paris VI) and Paris Diderot (Paris VII).
Next course: October 9-20, 2017
School in “Human Population Genomics and Genetic Epidemiology”
The first week consists in three days of both theoretical lectures and research examples, and two days of hands-on-computer training and discussions presenting the concepts and the technical tools used in both human population genomics and genetic epidemiology.
Topics include :
- Introductory concepts in human genomics and populations genetics.
- Basic concepts in statistical genetics and genomics.
- Introduction to genetic epidemiology.
- Population genetics: mutation, recombination and linkage disequilibrium.
- Public databases in human genomics (HapMap, 1,000 Genomes).
- Genetic epidemiology (linkage analyses and association studies).
- Methods to detect natural selection in the human genome.
- Research examples.
- Lectures from keynote speakers in genetic epidemiology and population genetics.
The second week consists in two days of detailed theoretical bases in population genomics and genetic epidemiology analyses and three days of practical computer-based training in the most recent concepts and analyses used in both disciplines. The practical training (computer laboratory work and discussion of the results) is based on real-data examples, using as a paradigm infectious diseases.
Topics include :
- Quantitative genetics and expression quantitative trait loci (eQTL) analysis.
- Analysis of rare variants and population structure.
- Next Generation Data – design and analysis.
- Genome-wide association analyses (GWAS) – exomes – whole genome sequencing – transcriptomics - RNA seq.
- Computer laboratory work in genetic epidemiology.
- Computer laboratory work in population genetics.
- Lectures from keynote speakers.
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Trainings and Seminars
- Journée de la Recherche Translationnelle (Translational Research Day)
The Center for Human Immunology (CIH) has established an annual symposium, entitled “Journée de la Recherche Translationnelle” (Translational Research Day).
The goal of this symposium is to promote and nucleate a community for basic scientists interested in medically relevant research and clinicians committed to expanding our scientific knowledge of disease. In addition, we aim to encourage students and medical fellows to pursue a career in translational research. Since its creation, the symposium mixes talks from international leaders in the
field of Translational Research and has provided a forum to present and discuss ongoing research projects in the CIH.
- Training opportunities
The Milieu Interieur project promotes the training of the next generation of scientists and has available positions for master 2 students. Please send your CV and cover letter to firstname.lastname@example.org