The Milieu Intérieur Consortium has established a 1,000-person healthy donor population, creating an unparalleled opportunity for assessing the determinants of human immunologic variance.
1,000 healthy donors
The Milieu Intérieur Consortium initiated in September 2012 a 1,000 person population-based study in order to assess the determinants of immunologic variance within the general healthy population "Genetic & Environmental Determinants Of Immune Phenotype variance: Establishing A Path Towards Personalized Medicine (ID-RCB Number: 2012-A00238-35)".
A de novo study-group of 1,000 healthy individuals (1:1 sex ratio) stratified across five-decades of life (age 20 – 70) from French-descent and recruited as per a detailed medical questionnaire has been recruited between September 17th, 2012 and August 8th, 2013.
The Milieu Intérieur study - an integrative approach for study of human immunological variance. Stéphanie Thomas, Vincent Rouilly, Etienne Patin, Cécile Alanio, Annick Dubois, Cécile Delval, Louis-Guillaume Marquier, Nicolas Fauchoux, Seloua Sayegrih, Muriel Vray, Darragh Duffy, Lluis Quintana-Murci, Matthew L. Albert, for The Milieu Intérieur Consortium. 2015 Jan 3. pii: S1521-6616(14)00271-X. doi: 10.1016/j.clim.2014.12.004. [Epub ahead of print]